Severe acute respiratory syndrome
Identifieur interne : 005067 ( Main/Exploration ); précédent : 005066; suivant : 005068Severe acute respiratory syndrome
Auteurs : J S M. Peiris ; Y. Guan ; K Y YuenSource :
- Nature Medicine [ 1078-8956 ] ; 2004.
Descripteurs français
- KwdFr :
- Animaux, Antiviraux (usage thérapeutique), Contrôle des maladies contagieuses, Flambées de maladies, Humains, Immunisation passive, Maladies transmissibles émergentes, Modèles biologiques, Santé mondiale, Syndrome respiratoire aigu sévère (), Syndrome respiratoire aigu sévère (diagnostic), Syndrome respiratoire aigu sévère (épidémiologie), Vaccination, Zoonoses.
- MESH :
- diagnostic : Syndrome respiratoire aigu sévère.
- usage thérapeutique : Antiviraux.
- épidémiologie : Syndrome respiratoire aigu sévère.
- Animaux, Contrôle des maladies contagieuses, Flambées de maladies, Humains, Immunisation passive, Maladies transmissibles émergentes, Modèles biologiques, Santé mondiale, Syndrome respiratoire aigu sévère, Vaccination, Zoonoses.
English descriptors
- KwdEn :
- Animals, Antiviral Agents (therapeutic use), Communicable Disease Control, Communicable Diseases, Emerging, Disease Outbreaks, Global Health, Humans, Immunization, Passive, Models, Biological, Severe Acute Respiratory Syndrome (diagnosis), Severe Acute Respiratory Syndrome (epidemiology), Severe Acute Respiratory Syndrome (prevention & control), Vaccination, Zoonoses.
- MESH :
- chemical , therapeutic use : Antiviral Agents.
- diagnosis : Severe Acute Respiratory Syndrome.
- epidemiology : Severe Acute Respiratory Syndrome.
- prevention & control : Severe Acute Respiratory Syndrome.
- Animals, Communicable Disease Control, Communicable Diseases, Emerging, Disease Outbreaks, Global Health, Humans, Immunization, Passive, Models, Biological, Vaccination, Zoonoses.
Abstract
Severe acute respiratory syndrome (SARS) was caused by a previously unrecognized animal coronavirus that exploited opportunities provided by 'wet markets' in southern China to adapt to become a virus readily transmissible between humans. Hospitals and international travel proved to be 'amplifiers' that permitted a local outbreak to achieve global dimensions. In this review we will discuss the substantial scientific progress that has been made towards understanding the virus—SARS coronavirus (SARS-CoV)—and the disease. We will also highlight the progress that has been made towards developing vaccines and therapies The concerted and coordinated response that contained SARS is a triumph for global public health and provides a new paradigm for the detection and control of future emerging infectious disease threats.
Url:
DOI: 10.1038/nm1143
PubMed: 15577937
PubMed Central: 7096017
Affiliations:
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Peiris</name><affiliation><nlm:aff id="Aff1">Department of Microbiology, The University of Hong Kong, University Pathology Building, Queen Mary Hospital, Pokfualm, Hong Kong Special Administrative, Region of China</nlm:aff><wicri:noCountry code="subfield">Region of China</wicri:noCountry></affiliation></author><author><name sortKey="Guan, Y" sort="Guan, Y" uniqKey="Guan Y" first="Y" last="Guan">Y. Guan</name><affiliation><nlm:aff id="Aff1">Department of Microbiology, The University of Hong Kong, University Pathology Building, Queen Mary Hospital, Pokfualm, Hong Kong Special Administrative, Region of China</nlm:aff><wicri:noCountry code="subfield">Region of China</wicri:noCountry></affiliation></author><author><name sortKey="Yuen, K Y" sort="Yuen, K Y" uniqKey="Yuen K" first="K Y" last="Yuen">K Y Yuen</name><affiliation><nlm:aff id="Aff1">Department of Microbiology, The University of Hong Kong, University Pathology Building, Queen Mary Hospital, Pokfualm, Hong Kong Special Administrative, Region of China</nlm:aff><wicri:noCountry code="subfield">Region of China</wicri:noCountry></affiliation></author></analytic><series><title level="j">Nature Medicine</title><idno type="ISSN">1078-8956</idno><idno type="eISSN">1546-170X</idno><imprint><date when="2004">2004</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Animals</term><term>Antiviral Agents (therapeutic use)</term><term>Communicable Disease Control</term><term>Communicable Diseases, Emerging</term><term>Disease Outbreaks</term><term>Global Health</term><term>Humans</term><term>Immunization, Passive</term><term>Models, Biological</term><term>Severe Acute Respiratory Syndrome (diagnosis)</term><term>Severe Acute Respiratory Syndrome (epidemiology)</term><term>Severe Acute Respiratory Syndrome (prevention & control)</term><term>Vaccination</term><term>Zoonoses</term></keywords><keywords scheme="KwdFr" xml:lang="fr"><term>Animaux</term><term>Antiviraux (usage thérapeutique)</term><term>Contrôle des maladies contagieuses</term><term>Flambées de maladies</term><term>Humains</term><term>Immunisation passive</term><term>Maladies transmissibles émergentes</term><term>Modèles biologiques</term><term>Santé mondiale</term><term>Syndrome respiratoire aigu sévère ()</term><term>Syndrome respiratoire aigu sévère (diagnostic)</term><term>Syndrome respiratoire aigu sévère (épidémiologie)</term><term>Vaccination</term><term>Zoonoses</term></keywords><keywords scheme="MESH" type="chemical" qualifier="therapeutic use" xml:lang="en"><term>Antiviral Agents</term></keywords><keywords scheme="MESH" qualifier="diagnosis" xml:lang="en"><term>Severe Acute Respiratory Syndrome</term></keywords><keywords scheme="MESH" qualifier="diagnostic" xml:lang="fr"><term>Syndrome respiratoire aigu sévère</term></keywords><keywords scheme="MESH" qualifier="epidemiology" xml:lang="en"><term>Severe Acute Respiratory Syndrome</term></keywords><keywords scheme="MESH" qualifier="prevention & control" xml:lang="en"><term>Severe Acute Respiratory Syndrome</term></keywords><keywords scheme="MESH" qualifier="usage thérapeutique" xml:lang="fr"><term>Antiviraux</term></keywords><keywords scheme="MESH" qualifier="épidémiologie" xml:lang="fr"><term>Syndrome respiratoire aigu sévère</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Animals</term><term>Communicable Disease Control</term><term>Communicable Diseases, Emerging</term><term>Disease Outbreaks</term><term>Global Health</term><term>Humans</term><term>Immunization, Passive</term><term>Models, Biological</term><term>Vaccination</term><term>Zoonoses</term></keywords><keywords scheme="MESH" xml:lang="fr"><term>Animaux</term><term>Contrôle des maladies contagieuses</term><term>Flambées de maladies</term><term>Humains</term><term>Immunisation passive</term><term>Maladies transmissibles émergentes</term><term>Modèles biologiques</term><term>Santé mondiale</term><term>Syndrome respiratoire aigu sévère</term><term>Vaccination</term><term>Zoonoses</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><p id="Par1">Severe acute respiratory syndrome (SARS) was caused by a previously unrecognized animal coronavirus that exploited opportunities provided by 'wet markets' in southern China to adapt to become a virus readily transmissible between humans. Hospitals and international travel proved to be 'amplifiers' that permitted a local outbreak to achieve global dimensions. In this review we will discuss the substantial scientific progress that has been made towards understanding the virus—SARS coronavirus (SARS-CoV)—and the disease. We will also highlight the progress that has been made towards developing vaccines and therapies The concerted and coordinated response that contained SARS is a triumph for global public health and provides a new paradigm for the detection and control of future emerging infectious disease threats.</p></div></front><back><div1 type="bibliography"><listBibl><biblStruct><analytic><author><name sortKey="Smith, Md" uniqKey="Smith M">MD Smith</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Shortridge, Kf" uniqKey="Shortridge K">KF Shortridge</name></author><author><name sortKey="Stuart Harris, Ch" uniqKey="Stuart Harris C">CH Stuart-Harris</name></author></analytic></biblStruct><biblStruct></biblStruct><biblStruct><analytic><author><name sortKey="Tsang, Kw" uniqKey="Tsang K">KW Tsang</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Lee, N" uniqKey="Lee N">N 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Olsen</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Sui, J" uniqKey="Sui J">J Sui</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Ter Muelen, J" uniqKey="Ter Muelen J">J Ter Muelen</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Traggian, E" uniqKey="Traggian E">E Traggian</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Soo, Yoy" uniqKey="Soo Y">YOY Soo</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Smolinski, Ms" uniqKey="Smolinski M">MS Smolinski</name></author><author><name sortKey="Hamburg, Ma" uniqKey="Hamburg M">MA Hamburg</name></author><author><name sortKey="Lederberg, J" uniqKey="Lederberg J">J Lederberg</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Li, Ks" uniqKey="Li K">KS Li</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Mackenzie, Js" uniqKey="Mackenzie J">JS Mackenzie</name></author><author><name sortKey="Field, Hf" uniqKey="Field H">HF Field</name></author><author><name sortKey="Guyatt, Kj" uniqKey="Guyatt K">KJ Guyatt</name></author></analytic></biblStruct><biblStruct></biblStruct><biblStruct><analytic><author><name sortKey="Singer, Pa" uniqKey="Singer P">PA Singer</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="O Neill, O" uniqKey="O Neill O">O O'Neill</name></author></analytic></biblStruct><biblStruct></biblStruct><biblStruct><analytic><author><name sortKey="Fidler, Dp" uniqKey="Fidler D">DP Fidler</name></author></analytic></biblStruct></listBibl></div1></back></TEI><affiliations><list></list><tree><noCountry><name sortKey="Guan, Y" sort="Guan, Y" uniqKey="Guan Y" first="Y" last="Guan">Y. 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